AI-guided antibody Development
Make your complex biologics happen.
Cradle helps scientists get to clinically viable candidates that meet every property in your TPP, with fewer programs lost along the way.
The next generation of biologics needs more than affinity
Your team is being asked to deliver biologics with binding profiles, formats, and developability constraints that single-property optimization can't reach. Bispecifics that hold both arms together at temperature. ADCs that survive payload conjugation without aggregating. Multispecifics with humanness, low immunogenicity, and clean PK. Hard targets where binding is only step one.
Antibody development before
Antibody development with Cradle
From hit to clinical-ready antibody, in fewer rounds.
Binding
KD, kon, koff, specificity, cross-reactivity, pH-dependent binding
Stability
Thermostability (Tm), aggregation, viscosity
Manufacturability
Expression yield, hydrophobicity (HIC)
Immunogenicity
Humanness, T-cell epitope risk, MHC binding
Developability
PTM liabilities (isomerization, deamidation, oxidation), polyspecificity
CASE STUDIES
6 of the top 25 pharma companies already use Cradle.
"Cradle's platform provides us with scalable scientist-centric solutions to maximize the opportunities in our biologics portfolio and potentially deliver faster, more effective medicines to patients."
Anastasia Hager, Ph.D.
Global Head of Drug Discovery Sciences, Bayer
Unlimited seats
Web Interface
For biologists
Add your domain expertise and AI generate candidates for lab testing in just a few clicks. Upload experimental results to improve your project-specific AI automatically.
API Access
For computational teams
Run Cradle with an API and scale your expertise without the DevOps overhead. Focus on novel design strategies, not routine requests and endless configuration.
Ready to get to clinical faster?
Talk to the Cradle team.
