BIOPHARMA
AI-assisted drug discovery for any biologic
Trusted by scientists at
Novo Nordisk,
Johnson & Johnson, and more.
Accelerate your path to Target Product Profile with Cradle’s protein design software platform. Generate proteins that meet multiple objectives, powered by your data and expertise.
Drug discovery before
Drug discovery with Cradle
Good bye sequential, hello simultaneous
Generate proteins that perform better across multiple properties, in every design cycle.
Optimize multiple objectives at once
Set the required objectives for your protein. Then generate proteins that satisfy these objectives, improving activity and developability in every design cycle.
De-risk earlier
Generate sequences that are free from undesirable motifs. Avoid post-translational modifications and eliminate immunogenicity or toxicity liabilities before taking your designs to the lab.
Design for real-world function
Don’t stop at binding. Incorporate data from downstream functional assays—including cell surface binding, reporter signaling, or cAMP assays—to guide the next round of optimization.
Train Cradle across your datasets
Connect all your experimental results in one place and train custom AI to learn more from your data.
Works with any format and assay
Cradle plays well with your experimental data - no matter the source. Import NGS data from screening campaigns, or raw experimental results from downstream assays.
Train AI throughout your program
Connect the dots and maximize learning throughout your program and across your organization. From early discovery datasets to your final assays, and from positive hits to negative results, Cradle ensures that no experimental data goes to waste.
No historical data? No problem.
Start a new program with as little data as a single sequence.
Protein design at any level of expertise
Use Cradle with simple defaults, or set advanced design requirements based on your in-house expertise.
Simple workflows
Run Cradle through its user interface, or exercise more control via the API. Don’t have extensive computational expertise? No problem–we have a team of advisors and engineers to help guide your approach.
Mutations where you want them
Specify where to allow changes in your protein - whether on the surface, in antibody CDRs or regions that you define. You can apply precise rules to steer clear of known liability motifs and ensure that sequences are compatible with downstream reformatting or conjugation.
AI your whole team understands.
Quickly generate clear, actionable reports to analyze your data and understand model performance, giving you the confidence you need before taking sequences into the lab.
Works on any biologic and all properties
Working on something not listed? If you can measure it there's a good chance Cradle can help you speed up the path to your program goals. Contact our sales team to discuss your specific needs.
If you can measure it, chances are Cradle's platform can help you progress faster. Talk to a Cradle expert to learn what Cradle can do for your organization.
Case studies
Design in Cradle.
Validate in the lab.
Design with generative AI customized to your biologic and run experiments like you always do.
Privacy-first AI
Your experimental data is only used to train your organization's custom models.
SOC 2 compliant
Cradle is fully SOC 2 compliant with active monitoring and tight security protocols in place.
Single sign-on
Secure and simple account management with SSO support for Google and Microsoft.
Custom predictors
BETA
Use internally developed predictors right in Cradle and see outputs inside Reports.
Zero-maintenance
Fully managed AI infrastructure with optimized GPUs that scale with your needs.
