Optimizing CRISPR on-target activity to 75% while reducing off-target editing 4-fold

Engineering CRISPR on-target editing activity from <25% to 68% in three rounds

Using AI to produce vaccine adjuvants without cutting down rainforest

Visualizing trade-offs in multi-property protein optimization

Drug discovery leader Marcus Schindler joins Cradle’s Advisory Board

We put our CTO in a lab coat. Here’s what happened next.

Engineering therapeutic peptides with 50% success rate under tight multi-property constraints, 5× faster than prior efforts

Improving Staphylococcus aureus vaccine thermostability by 2.5 °C in a single round, 7× faster than rational design

Rescuing a stalled IgG campaign: 10 candidates meeting potency and developability criteria in 3 rounds

Improving haloalkane dehalogenase thermostability by +20 °C while enhancing activity and expression

Engineering polyspecific anti-venom VHHs with sub-nanomolar binding and high thermostability

Engineering polyspecific VHHs with picomolar binding to SARS-CoV-2 wild type and Omicron

Bayer and Cradle enter collaboration to enhance AI-enabled antibody discovery and optimization

Cradle AI-powered protein engineering platform serving six of top 25 pharma leaders

Backbone of high-throughput experimentation: Design principles for ML-ready sample tracking

Lab automation for faster ML-driven protein engineering

We were intentional about our company culture from day one. Here’s why that matters.

Is your drug discovery ready for AI? A maturity model for GenAI in drug discovery [Live webinar]

From lab rat to data detective: How this scientist turned Sales into an art form.

Cradle’s innovation engine: How benchmarking powers breakthrough protein design

Optimizing Cetuximab: An update on our win of the Adaptyv 2024 competition

Cradle Announces Launch of Advanced Biotechnology Report with Industry Coalition

Next-level high throughput workflows: Gotta tag 'em all

SLAS 2025: A Peek at The Future of Lab Automation

8x improvement in EGFR binding affinity: winning the Adaptyv Bio protein design competition

Cradle raises $73M Series B to Put AI-Powered Protein Engineering in Every Lab

We're Funding the Creation of an Open-Source Antibody Dataset

'Align to Innovate' benchmark: state-of-the-art enzyme engineering with fully-automated GenAI

Cultural values at Cradle

We Welcome Sam Partovi as Our Chief Commercial Officer

Affordable High-Throughput Protein Purification

The Art of Assays, Part 2: Tips and Tricks for Developing Great Assays

The Art of Assays, Part 1: Insights From Our Lab Into Enzymatic Assay Development

Designing the future, one protein at a time: A chat with Franzi

From Prisons to Proteins: The Unexpected Journey of a UX Researcher

Cradle partners with Google Cloud on security for protein engineering.

The Rise of The Pioneers. Innovating with Proteins to Transform Industries. Part 2.

From Bench to Bytes: Why This Protein Engineer Joined an AI Startup, an Interview with Jinel Shah

The Rise of The Pioneers. Innovating with Proteins to Transform Industries. Part 1.

Exploring Darwin Assembly: Insights from Cradle's Research on Efficient Gene Mutagenesis

Synthetic Symphonies: How an Audio Expert is Revolutionizing Biotech with AI, an Interview with Jonathan.

Case study: design better P450s 4X faster by combining AI-generated mutations with human expertise

Cradle partners with Ginkgo and becomes part of the Ginkgo Technology Network

How to Get Started Using AI for Protein Design: A Guide to Data Collection

Cradle raises $24M Series A and signs partnerships with industry leaders

2022 Bio Developer survey results

We've raised $5.5M to design protein-machines and cell-factories with AI